Assayed LDL-Cholesterol
Al Borg Laboratory has recently introduced "assayed” LDL-Cholesterol which gives true & precise
patient results.Most labs use “mathematically calculated” LDL and presume that a direct relationship
exists between VLDL-cholesterol and Triglycerides. This assumption is incorrect and their calculated
LDL-Cholesterol is falsely low.

High Sensitive CRP (HS CRP)
CRP is a protein released into the blood in response to active inflammation. Evidence is accumulating
that atherosclerosis is an inflammatory process. Recent studies show that a moderate elevation in
(HS CRP) correlates with future cardiovascular events hence its value to assess cardiovascular risk.

Homocysteine

Is a Sulphur-containing amino acid produced from methionine that reflects dietary protein intake and

turnover.Four vitamins are involved in homocysteine metabolism.

Causes of elevated Homocysteine?

• Congenital Homocysteinuria
• High protein diet with low folate, B12, B6, B2, Zinc or Copper.
• Diseases (Hypothyroidism, Renal failure, Hepatic insufficiency, Acute leukemia,
  Psoriasis, Systemic Lupus..)
• Drugs (Oral anti glycemics, Contraceptive pills, Anti epileptics, Anti hypercholesterolemic
  drugs, Methotrexate, Nitrous oxide..)

Effects of elevated Homocysteine?

Elevated concentrations of Homocysteine result in blood vessel injury through altering
endothelial and smooth muscle function by reacting directly with cellular constituents.

Conclusion
13%-42% of Coronary Heart Disease risk appears attributable to elevated serum Homocysteine
hence should be included routinely with the other laboratory risk factors. TSH should also be assayed

in patients with unexplained elevated Homocysteine and Cholesterol